• PhD fellowship in “Molecular Mechanisms of Antibacterial Action and Resistance of Novel Antibacterial Agents”

    PhD fellowship in “Molecular Mechanisms of Antibacterial Action and Resistance of Novel Antibacterial Agents” at the Department of Microbial Bioactive Compounds, Interfaculty Institute of Microbiology…

  • New paper! An antibiotic from an uncultured bacterium binds to an immutable target

    Antimicrobial resistance is a leading mortality factor worldwide. Here, we report the discovery of clovibactin, an antibiotic isolated from uncultured soil bacteria. Clovibactin efficiently kills drug-resistant…

  • New paper! Molecular Characterization of the ClpC AAA+ ATPase in the Biology of Chlamydia trachomatis

    Chlamydia trachomatis is an obligate intracellular pathogen and the…

  • Kinder-Uni-Forschungstag: Das Unsichtbare sichtbar machen: Mikrobiologie Mitmach-Workshop im Schloss

    Gemeinsam mit Wissenschaftlern des Exzellenzclusters CMFI und TRR261 wurde am ersten Juli das Unsichtbare sichtbar! Im Rahmen des Workshops wurden einfache Techniken aus dem Zell- und Mikrobiologielabor…

  • New TRR paper! Identification of macrocyclic peptides which activate bacterial cylindrical proteases

    The caseinolytic protease complex ClpXP is an important house-keeping enzyme in prokaryotes charged with the removal and degradation of misfolded and aggregated proteins and performing regulatory proteolysis.…

  • International Conference TRR261, 22-25 May, 2023 in Bad Boll

    We enjoyed the excellent talks and posters, great science and unforgettable networking!

    Many thanks to all participants for the amazing…

  • New TRR-publication! Inhibition of peptidoglycan synthesis is sufficient for total arrest of staphylococcal cell division

    Researchers from Bonn clarify inhibitory effect mechanism of antibiotics on the growth of Staphylococcus aureus
  • Harald Gross receives the 2022 PHOENIX Pharmaceutical Science Award in the category Pharmaceutical Biology

    The pharmacist is, together with the two further TRR members Evi Stegmann and Wolfgang Wohlleben, honored for the biotechnological development of a production platform…

  • World Antimicrobial Awareness Week 2022

    Gemeinsam gegen Antibiotika-Resistenzen

    Antibiotika sind bis heute unsere wichtigste Waffe gegen bakterielle Infektionen. Jedoch verlieren sie zunehmend an Wirkung, da Antibiotikaresistenzen…

  • New TRR-publication! The Substrate Scope of Dehydratases in Antibiotic Biosynthesis and their Application in Kinetic Resolutions

    Congratulations to Zhiyong Yin,  Daniel Baer, Bertolt Gust and Jeroen Dickschat on their recent publication!