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New TRR-publication! Inhibition of peptidoglycan synthesis is sufficient for total arrest of staphylococcal cell division
Researchers from Bonn clarify inhibitory effect mechanism of antibiotics on the growth of Staphylococcus aureus
Harald Gross receives the 2022 PHOENIX Pharmaceutical Science Award in the category Pharmaceutical Biology
The pharmacist is, together with the two further TRR members Evi Stegmann and Wolfgang Wohlleben, honored for the biotechnological development of a production platform…
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World Antimicrobial Awareness Week 2022
Gemeinsam gegen Antibiotika-Resistenzen
Antibiotika sind bis heute unsere wichtigste Waffe gegen bakterielle Infektionen. Jedoch verlieren sie zunehmend an Wirkung, da Antibiotikaresistenzen…
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New TRR-publication! The Substrate Scope of Dehydratases in Antibiotic Biosynthesis and their Application in Kinetic Resolutions
Congratulations to Zhiyong Yin, Daniel Baer, Bertolt Gust and Jeroen Dickschat on their recent publication!
New TRR-publication! Antibiotic Acyldepsipeptides Stimulate the Streptomyces Clp-ATPase/ClpP Complex for Accelerated Proteolysis
Clp proteases consist of a proteolytic, tetradecameric ClpP core and AAA+ Clp-ATPases. Streptomycetes, producers of a plethora of secondary metabolites, encode up to five different… More
Annika Krüger receives Sigrid Peyerimhoff-Award
It is our great pleasure to announce that Annika Krüger received the Sigrid Peyerimhoff-Preis 2022! As a MSc-student from the University of Bonn (Prof. Dr. Kubitscheck’s research group) she received…
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TRR 261 PhD Meeting 2022
In October, PhDs and PostDocs from Bonn and Tübingen met at the Gustav-Stresemann-Institute in Bonn to connect, present, and discuss their latest results. Accompanied by four excellent external…
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New TRR paper! Antibacterial Synnepyrroles from Human-Associated Nocardiopsis sp. Show Protonophore Activity and Disrupt the Bacterial Cytoplasmic Membrane
Actinobacteria have traditionally been an important source of bioactive natural products, although many genera remain poorly explored. Here, we report a group of distinctive pyrrole-containing natural…
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New TRR publication! Cervimycin-Resistant Staphylococcus aureus Strains Display Vancomycin-Intermediate Resistant Phenotypes
Resistance to antibiotics is an increasing problem and necessitates novel antibacterial therapies. The polyketide antibiotics cervimycin A to D are natural products of More
