New TRR-paper! Compendium of specialized metabolite biosynthetic diversity encoded in bacterial genomes
Congratulations to Athina Gavriilidou, Satria Kautsar, Nestor Zaburannyi, Daniel Krug, Rolf Müller, Marnix Medema and Nadine Ziemert!
By analyzing a huge number of bacterial genomes for potentially…More
New TRR-publication! Versatile synthesis of pathogen specific bacterial cell wall building blocks
Congratulations to Lukas Martin Wingen, Christina Braun, Marvin Rausch, Harald Gross, Tanja Schneider and Dirk Menche!
A modular three coupling strategy involving a versatile solid phase peptide…More
New TRR-paper! Structural insights into ClpP protease side exit pore-opening by a pH drop coupled with substrate hydrolysis.The catalytic cycle of ClpP is dynamic and ADEP helped to shed further light on the details and intermittent stages: Delineating the mechanisms of substrate engagement and product release … More
New TRR-paper! A data management infrastructure for the integration of imaging and omics data in life sciences
Authors describe a data management architecture for integrated, FAIR-supporting management of omics and biomedical imaging data, and exemplify its applicability for basic biology research and clinical…More
New TRR publication! Synergetic Antimicrobial Activity and Mechanism of Clotrimazole-Linked CO-Releasing Molecules
In a collaborative effort, several of our TRR members unraveled the multi-layered mode of action of a new clotrimazole-linked carbon-monoxide releasing antibacterial agent. Congratulations to all authors!