News
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New TRR-publication! Versatile synthesis of pathogen specific bacterial cell wall building blocks
Congratulations to Lukas Martin Wingen, Christina Braun, Marvin Rausch, Harald Gross, Tanja Schneider and Dirk Menche!
A modular three coupling strategy involving a versatile solid phase peptide…
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New TRR-paper! Structural insights into ClpP protease side exit pore-opening by a pH drop coupled with substrate hydrolysis.
The catalytic cycle of ClpP is dynamic and ADEP helped to shed further light on the details and intermittent stages: Delineating the mechanisms of substrate engagement and product release … More
New TRR-paper! A data management infrastructure for the integration of imaging and omics data in life sciences
Authors describe a data management architecture for integrated, FAIR-supporting management of omics and biomedical imaging data, and exemplify its applicability for basic biology research and clinical…
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New TRR publication! Synergetic Antimicrobial Activity and Mechanism of Clotrimazole-Linked CO-Releasing Molecules
In a collaborative effort, several of our TRR members unraveled the multi-layered mode of action of a new clotrimazole-linked carbon-monoxide releasing antibacterial agent. Congratulations to all authors!
New paper! An Isotopic Probe to Follow the Stereochemical Course of Dehydratase Reactions in Polyketide and Fatty Acid Biosynthesis
New TRR-paper on dehydratases! Congratulations to all authors! Four stereoisomeric and isotopically labelled probes that are suitable to easily follow the stereochemical course of dehydratases have…
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