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New TRR261-publication! The hypersusceptible antibiotic screening strain Staphylococcus aureus SG511-Berlin harbors multiple mutations in regulatory genes
The genetic plasticity of Staphylococcus aureus has facilitated the evolution of many virulent and drug-resistant strains. Here we present the sequence of the 2.74 Mbp genome of S. aureus SG511-Berlin,…
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TRR261 GOES BLUE!
TRR261 goes blue :
• To make AMR a globally recognized issue with engagement of all sectors - human, animal, plant and environment, a 'One Health approach'.
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• To raise awareness of the need… -
Spitzenforschung trifft Politik!
Gelungener Austausch mit Annette Widmann-Mauz zur Forschung im Bereich Mikrobiologie/Infektionsforschung Tübinger und überregionaler Forschungsverbünde…
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New paper! THCz: Small molecules with antimicrobial activity that block cell wall lipid intermediates
Considering the alarming emergence of resistance to most antibiotics and the need for new antibiotics, the finding here of a small-molecule class, THCz, that displayed bactericidal activity…
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World Antimicrobial Awareness Week 2021
Antibiotics are the heart of health
Antibiotics have revolutionised medicine and saved millions of lives in the past 8 decades.…
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"Den körpereigenen Schutzschild aktivieren" — Prof. H. Brötz-Oesterhelt was a guest of the regional newspaper
Our TRR261-CellMAP Spokesperson, Prof. Heike Brötz-Oesterhelt, was a guest of the week in the Newspaper Schwäbisches Tagblatt .
The interview concerned following topics: how we deal…
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New paper! Activation and Identification of a Griseusin Cluster in Streptomyces sp. CA-256286 by Employing Transcriptional Regulators and Multi-Omics Methods
Streptomyces are well-known producers of a range of different secondary metabolites, including antibiotics and other bioactive compounds. Recently, it has been demonstrated…
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New publication! Contribution of the Clp Protease to Bacterial Survival and Mitochondrial Homoeostasis.
Fast adaptation to environmental changes ensures bacterial survival, and proteolysis represents a key cellular process in adaptation. The Clp protease system is a multi-component machinery responsible…
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New paper! Host Defense Peptides: Dual Antimicrobial and Immunomodulatory Action
The rapid rise of multidrug-resistant (MDR) bacteria has once again caused bacterial infections to become a global health concern. Antimicrobial peptides (AMPs), also known as host defense peptides…
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