New TRR-paper! Compendium of specialized metabolite biosynthetic diversity encoded in bacterial genomes
Congratulations to Athina Gavriilidou, Satria Kautsar, Nestor Zaburannyi, Daniel Krug, Rolf Müller, Marnix Medema and Nadine Ziemert!
By analyzing a huge number of bacterial genomes for potentially encoded natural products the authors conclude that only a very small portion has been experimentally characterized yet. Furthermore, they show that the variation in secondary metabolite biosynthetic diversity drops significantly at the genus level, identifying it as an appropriate taxonomic rank for comparison.
The research paper can be accessed under: https://doi.org/10.1038/s41564-022-01110-2