Synthesis of Tetramic Acid Fragments Derived from Vancoresmycin Showing Inhibitory Effects towards S. aureus

Synthesis of Tetramic Acid Fragments Derived from Vancoresmycin Showing Inhibitory Effects towards S. aureus

Dirk Menche (Project B07) and Tanja Schneider (A09, A10) published their work on the total synthesis of new antibacterial vancoresmycin-type tetramic acids and initial studies on the mechanism of action in ChemMedChem. The article is featured in the new Special Collection on Antimicrobials (2020 Hot Topic Series), which is free to read for the rest of the year. Link